Covid-19 vaccination - anyone scheduled yet?

[Phil K]

I actually don't understand that conclusion or the conclusion in the interview Phil provided. In the trial, only 0.8% of the group that received the placebo became infected and only 0.04% of the group that received the vaccination became infected. That's more than 99% in both groups that did not become infected. Yet only 90% of the non-controlled, much larger group that was studied in Israel did not become infected. How are the results of the two studies being considered about the same, not that I'm complaining about 90% effectiveness at preventing infection and 100% preventing hospitalization and death?

What am I missing (other than a glass of wine)?

We cannot directly compare the numbers in 2 different studies because of differences in study designs and many variables. Maybe you can read the discussion section in the full paper which explains the results more clearly.
https://www.nejm.org/doi/pdf/10.1056/NEJMoa2101765?articleTools=true

 

[Mike Buckley]

We cannot directly compare the numbers in 2 different studies because of differences in study designs and many variables.

The two people in the audio interview that you provided compared those numbers and concluded that the results of the two studies were about the same. The original article you provided also states that "This study in a nationwide mass vaccination setting suggests that the BNT162b2 mRNA vaccine is effective for a wide range of Covid-19–related outcomes, a finding consistent with that of the randomized trial." (Bold font added by me to convey emphasis)

 

[Butlerkid]

Wednesday night Mom (90 years old living alone in Calif) told me the local Walgreen's was giving the vaccines. (The STATE site kept saying her nearest location was 25+ miles away....) I set up a Walgreen's account selecting the store about 4 miles from her. I used her name, my email, her phone number and started checking available dates. Nothing all Wed. night. Yesterday - Thursday morning I started checking again. Nothing. 1.5 hours later. Still nothing. 1.5 hrs later - ONE appt available. I grabbed it! Must have been a cancellation.....They also set up an appt for the 2nd shot. The vaccine date was TODAY.

Good thing there are alternatives to Calif government............. I've been checking there since early January.

 

[rhynetc]

Good job, Karen! As with Mars rovers, Perseverance pays off!

 

[ac12]

Wife got her 2nd shot today. yay
It was postponed due to delivery delay from the bad weather.

Now, I have to wait for my 2nd shot.

 

[nuclearjock]

This Tuesday 3/2/2021 first dose for me. Still kinda scarce around here. Moderna.

 

[RoyC01]

U.S. Vaccination Campaign Updated: February 27, 2021, 4:10 PM EST

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Jurisdiction	Doses administered	1+ dose	2 doses	Daily rate of doses administered	Supply used
		% of population given
U.S. Totals	72,806,180	14.6	7.1	1,645,240	75.5%
California	8,566,470	15.2	6.3	194,965	73.9%
Texas	5,394,961	12.4	6.2	111,466	70.8%
Florida	4,822,353	14.4	7.9	88,065	76.4%
New York	4,060,431	13.3	7.1	74,919	70.5%
Federal Entities*	3,792,872	–	–	90,846	76.5%
Illinois	2,735,250	15.4	5.9	67,681	76.5%
Pennsylvania	2,676,006	14.6	6.2	63,458	68.3%
Ohio	2,501,854	14.1	7.3	62,123	75.8%
North Carolina	2,366,027	14.5	8.0	51,031	79.3%
Michigan	2,245,696	14.2	8.0	51,665	83.0%
Georgia	2,070,076	12.1	7.0	40,474	71.8%
New Jersey	2,008,524	15.0	7.5	51,418	80.1%
Virginia	2,002,734	15.3	7.8	47,360	79.0%
Arizona	1,728,239	16.8	6.8	43,278	80.5%
Massachusetts	1,684,341	17.5	6.9	44,129	80.5%
Washington	1,666,839	14.5	7.2	37,087	74.2%
Indiana	1,551,945	14.7	8.1	45,361	84.0%
Wisconsin	1,421,435	16.1	8.1	33,258	89.5%
Colorado	1,324,715	15.2	7.6	22,403	77.9%
Minnesota	1,322,288	15.6	7.7	32,139	82.7%
Tennessee	1,301,529	12.5	6.5	29,100	66.2%
Maryland	1,280,675	13.7	7.4	32,315	69.7%
Missouri	1,278,087	13.6	7.1	33,602	75.4%
South Carolina	1,057,969	13.9	6.3	25,456	79.0%
Oklahoma	1,046,995	16.9	9.3	30,870	74.8%
Louisiana	1,019,381	14.0	7.9	20,243	76.5%
Kentucky	980,727	14.7	7.2	26,254	74.4%
Connecticut	980,211	18.9	8.3	18,913	81.8%
Oregon	960,674	14.7	8.0	23,699	77.4%
Alabama	931,090	12.8	6.1	22,022	66.4%
Utah	687,876	12.2	5.5	11,115	83.8%
Iowa	684,596	16.2	5.3	15,317	75.9%
New Mexico	678,087	21.0	11.0	14,167	91.8%
Nevada	665,577	14.4	7.1	15,691	76.7%
Arkansas	622,665	13.4	7.1	14,537	69.8%
Mississippi	593,453	13.4	6.5	16,004	68.2%
Kansas	583,498	13.5	6.3	13,537	67.3%
Puerto Rico	538,085	10.9	5.9	10,651	51.9%
West Virginia	526,059	17.9	11.5	9,710	86.9%
Nebraska	443,974	15.2	7.6	11,913	73.6%
Idaho	378,401	13.8	6.7	9,276	78.0%
Hawaii	370,746	17.0	9.1	8,288	74.5%
Maine	332,358	16.7	7.9	9,148	79.9%
New Hampshire	310,769	15.9	7.0	8,639	75.4%
Montana	271,075	17.1	8.2	6,026	79.3%
South Dakota	269,289	20.2	10.2	6,206	81.8%
Alaska	259,538	22.3	13.1	4,591	75.8%
Rhode Island	245,606	16.5	6.7	7,816	79.6%
North Dakota	225,330	19.2	10.1	5,262	91.4%
Delaware	212,739	14.8	7.0	4,591	72.9%
District of Columbia	184,748	17.1	9.0	3,587	64.9%
Vermont	156,929	16.7	8.4	3,545	75.8%
Wyoming	151,584	17.0	9.1	3,218	77.4%
Guam	54,244	20.6	11.8	837	105.7%
American Samoa	20,338	22.0	14.4	371	69.1%
U.S. Virgin Islands	19,118	12.2	6.1	470	53.0%
Northern Marianas	18,121	18.6	13.3	371	61.1%
Micronesia	14,317	10.1	3.6	390	47.7%
Marshall Islands	10,745	14.4	3.9	485	51.2%
Palau	8,143	28.4	17.1	307	88.5%
Unassigned*	280,650	–	–	4,477	–

 

[Butlerkid]

^^^

Interesting to see what % of of each state's supply has actually been USED!

 

[Mike Buckley]

My county reported as of February 21 that it had administered 96% of the doses it had received from the state. EDIT: As of February 28, the number increased to 97%.

 

[Hylander]

Got my first dose of Pfizer on Thursday.

 

[kilofoxtrott]

My wife, skilled care giver, will get her Pfizer on Thursday...

Klaus

 

[gchappel]

Interesting chart, thanks for posting.
Interesting that Guam has given out more doses than it received. 105%.
Gary

 

[Mike Buckley]

Interesting that Guam has given out more doses than it received. 105%.

The nurse of 37 years that vaccinated me told me that it's typical that vials contain slightly more medicine than the specified amount and that the same is true with most vaccines. That usually makes it possible to give out more doses than technically were provided.

 

[gchappel]

They actually can get 6 doses out of each 5 dose vialwith special dead space syringes. That research was actually done but Pfizer so they could call them 6 dose vials.
The problem right now is the dead space syringes are out of stock everywhere. Hard to believe in 2021 we still have syringes that waste product. Not just vaccine but all drugs. They do cost more to make, and I suppose it just was never important before.
Gary

 

[Mike Buckley]

dead space syringes

Too bad they don't make dead-space nozzles for my water drop kit.

 

[Bilbo7591]

Got my first shot last Thursday. Had a doc appointment already for minor surgery, they called & said someone had cancelled their appointment, would I like to get it & I did. No problems at all, just a sore spot on my shoulder. I was not supposed to get it until April per state schedule. My ex-wife in Florida had her 2nd 2 weeks ago, it knocked her down bad, sickest she has ever been.

 

[McQ]

I got the first Moderna shot and it went fine. Felt a little sore in the arm, and a little "off" for a day. Nothing bad, just a tad fuzzy. Everyone keeps telling me the second shot elicits more of a reaction. I don't care. Just happy to be getting them.

 

[Clix Pix]

Finally got an appointment for my second Moderna at a location near my home -- I was getting a little anxious since it was approaching the end of the recommended time period but all is well.

 

[Pa]

I was getting a little anxious since it was approaching the end of the recommended time period but all is well.

I think there is room for a good bit of wiggle in those recommendations. After all, in the UK they are delaying the second dose for up to two months.

My wife and I got our #2 two days earlier than the nominal date.

 

[Clix Pix]

Yes, that's what I've seen, too, that there is some wiggle room, thank goodness! There has been some discussion in the US, too, about delaying second doses and giving that vaccine to people as their first dose, but in the end the decision was to keep the status quo, especially as now there should be more vaccine supplies available with the addition of J&J's vaccine plus the Merck Company helping out with also manufacturing more. I will be happy when I've had that second Moderna jab (hopefully won't have a lot of reaction to it) and am done with this.